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Chicken Pesto Pasta Bake Recipe


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  • Author: Mira Vaughn
  • Total Time: 45 minutes
  • Yield: 6-8 servings 1x
  • Diet: Vegetarian

Description

This Chicken Pesto Pasta Bake combines tender chicken, perfectly cooked pasta, and vibrant basil pesto in a creamy, cheesy sauce. Topped with golden, bubbling mozzarella and Parmesan, it’s the ultimate comfort food that’s perfect for weeknight dinners or feeding a crowd. Simple ingredients transform into something truly special in this family-friendly casserole.


Ingredients

Scale
  • 1 pound penne or rigatoni pasta
  • 1.5 pounds boneless, skinless chicken breasts, cut into 1-inch pieces
  • 1 cup basil pesto (store-bought or homemade)
  • 1 cup heavy cream
  • 1/2 cup chicken broth
  • 2 cups shredded mozzarella cheese, divided
  • 1 cup freshly grated Parmesan cheese, divided
  • 1 cup cherry tomatoes, halved (optional)
  • 3 cloves garlic, minced
  • 2 tablespoons olive oil
  • 1 teaspoon Italian seasoning
  • Salt and black pepper to taste
  • Fresh basil leaves for garnish


Instructions

  1. Preheat your oven to 375°F (190°C). Lightly grease a 9×13-inch baking dish with cooking spray or a drizzle of olive oil and set aside.
  2. Cook the pasta according to package directions until al dente (it should still have a slight bite since it will continue cooking in the oven). Drain well and set aside. Pro tip: Reserve 1/2 cup of pasta water in case you need to thin the sauce later.
  3. Prepare the chicken by cutting it into uniform 1-inch pieces so they cook evenly. Season generously with salt, pepper, and Italian seasoning on all sides.
  4. Heat olive oil in a large skillet over medium-high heat. Once shimmering, add the chicken pieces in a single layer (work in batches if needed to avoid overcrowding). Cook for 4-5 minutes per side until golden brown and cooked through (internal temperature should reach 165°F). Remove chicken from the skillet and set aside.
  5. In the same skillet, reduce heat to medium and add minced garlic. Sauté for 30-60 seconds until fragrant but not browned. Pour in the chicken broth to deglaze the pan, scraping up any flavorful browned bits from the bottom.
  6. Create the sauce by stirring in the pesto and heavy cream. Mix until smooth and well combined. Let it simmer gently for 2-3 minutes until slightly thickened. Taste and adjust seasoning with salt and pepper if needed.
  7. Combine everything in a large mixing bowl. Add the cooked pasta, chicken pieces, pesto cream sauce, 1 cup of mozzarella, and 1/2 cup of Parmesan. If using cherry tomatoes, fold them in now. Toss everything together until the pasta and chicken are thoroughly coated with sauce.
  8. Transfer to baking dish and spread the mixture evenly. Top with the remaining 1 cup of mozzarella and 1/2 cup of Parmesan cheese, distributing it evenly across the surface.
  9. Cover with foil and bake for 20 minutes. This allows the flavors to meld and ensures the pasta doesn’t dry out.
  10. Uncover and finish baking for an additional 10 minutes, or until the cheese is golden brown and bubbling. For an extra-crispy top, broil for the last 2-3 minutes, watching carefully to prevent burning.
  11. Let it rest for 5 minutes before serving. This allows the sauce to thicken slightly and makes serving much easier. Garnish with fresh basil leaves and an extra sprinkle of Parmesan if desired.

Notes

  • Don’t skip the al dente cooking step for pasta—overcooked pasta will become mushy after baking.
  • For a lighter version, substitute half-and-half for heavy cream and reduce cheese by 25%.
  • This dish reheats beautifully—cover with foil and warm in a 350°F oven for 15-20 minutes.
  • Add extra veggies like spinach, sun-dried tomatoes, or roasted red peppers for more nutrition.
  • If the mixture seems dry before baking, add a splash of the reserved pasta water or extra chicken broth.

  • Prep Time: 15 minutes
  • Cook Time: 30 minutes
  • Category: Dinner
  • Method: Baking
  • Cuisine: Italian-American

Nutrition

  • Serving Size: 1 generous cup
  • Calories: 485
  • Sugar: 3g
  • Sodium: 620mg
  • Fat: 24g
  • Saturated Fat: 11g
  • Unsaturated Fat: 11g
  • Trans Fat: 0g
  • Carbohydrates: 38g
  • Fiber: 2g
  • Protein: 32g
  • Cholesterol: 95mg